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The timing of compounds, escalation schedules, and cycle architecture all influence outcomes

One proposed mechanism of action is that stimulation of 5-HT 2C receptors in pro-opiomelanocortin (POMC) neurons within the arcuate nucleus of the hypothalamus leads to increased release of -MSH (Garfield and Heisler, 2009)

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(2000) Prospective, randomized, controlled study of in vitro fertilizationembryo transfer with a single dose of a luteinizing hormone-releasing hormone (LH-RH) antagonist (cetrorelix) or a depot formula of an LH-RH agonist (triptorelin)