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VH variable heavy chain VL variable light chain variable domains of antibodies are not evenly distributed throughout the variable domains of antibodies

Ferroptosis, an iron-dependent form of RCD driven by GSH depletion and GPX4 inactivation, is potently accelerated by copper through multi-pronged mechanisms that converge on iron-dependent lipid peroxidation [61, 62]

163 Changes in T cell senescence are also associated with cognitive decline

Zhu H, Wang J, Zhang Q, Pan X, Zhang J

Concomitantly, another recent study has shown that a PARP inhibitor could limit the formation of omental metastasis from ovarian cancer cells through the upregulation of CD36, leading to ferroptosis induction [45]