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Determination of stability of NMY1009 and FCCP in aqueous buffer The quantification of NMY1009 and FCCP by by LCMS/MS was similar to the microsomal stability assays, except that the final drug concentration was 10 M and that myriocin was used as internal standard and mass spectrometry analysis of NMY1009 and FCCP was carried out in positive electrospray ionization (ESI) mode

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DOI.org (Crossref),

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Mammalian erythrocytes, unlike the erythrocytes of birds, amphibians and fishes, are enucleate and lack major cell organelles

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Interestingly, transfection of neurons with a cDNA construct, in which the pre-pro-domain of BDNF is fused to the mature part of the neurotrophin-4 (NT-4) redirects this BDNF-NT-4 chimera efficiently into vesicles of the regulated secretory pathway, whereas wildtype NT-4 is predominantly located in vesicles of the constitutive secretory pathway (Brigadski et al

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