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Your body has this whole system called the methylation pathway (fancy name, I know) that converts B12 into something your cells can actually use

Investigators have employed various techniques to assess stochastic gene expression and transcriptional bursting in particular and identify the associated molecular mechanisms: e.g., using single-molecule RNA single molecule fluorescence in situ hybridization (smRNA FISHFISH), using the MS2 green fluorescent protein to illuminate RNA stem loops by epifluorescence or confocal microscopy, and monitoring short-lived protein reporters allow the quantification of transcriptional bursting in particular

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M.FernandezD.et al

Regular health check-ups during therapy are recommended