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Large-scale randomised controlled trials, including the STEP 1 trial (Wilding et al., NEJM 2021) for semaglutide 2.4 mg, have demonstrated clinically meaningful and sustained weight loss in adults with obesity or overweight with weight-related comorbidities

Potential Benefits Improved body composition, including reduced body fat and increased lean muscle mass Better sleep quality through optimization of the bodys natural GH release cycles Enhanced energy levels and reduced daytime fatigue Improved cognitive function and memory support Anti-aging effects, including improvements in skin thickness and texture Support for patients with diabetes through reduced fatigue and improved body composition Glycine, an amino acid and neurotransmitter, is paired with Sermorelin to further optimize GH production

The antioxidant effect was demonstrated by improvements in parameters such as MDA, CAT and GSH levels and increased levels of the SOD enzyme (135,141)

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