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Additionally, a separate study discovered that purine metabolism, in addition to gluconeogenesis, plays a role in the advancement of fibrosis [164]

A small risk with intravenous formulations is allergic reactions, ranging from flushing, itching, swelling of the lips and throat to difficulty breathing and low blood pressure ( 23 )

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See Figure 1 a general schema with different targets on the peripheral nervous system and in Table 1 a list of them with their mechanism of neurotoxicity