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When prescribing these medications, caution should be used because of their extensive side-effect profiles and risk of addiction, misuse and abuse

Thus, TMAO may become a new diagnostic biomarker for heart failure and renal impairment

Acknowledgement The work was supported by a grant-in-aid project from the Department of Biotechnology (BT/PR39040/BRB/10/1882/2020) to AKB

Navitoclax (ABT-263) demonstrates anti-cancer properties, particularly when used with MEK or tyrosine kinase inhibitors against solid tumors (Tse et al., 2008