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Disruptions in circadian rhythms can adversely affect sleep quality and lead to imbalances in gut microbiota, resulting in alterations to the community structure, ecological parameters of the microbial ecosystem, and the inflammatory state of the body [45, 214,215,216,217,218,219,220,221]

Mice were placed in the maze for 5 min and recorded by video

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revealed that apoA I-mimetic peptide 5A could attenuate renal fibrosis and reduce macrophage infiltration in the UUO mice