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11beta-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments

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Further support for targeting the PDH complex is evidence that genetic inhibition of PDK confers cyanide resistance in zebrafish [66]

doi: 10.1016/j.neuron.2020.07.015 79 ZhangXLeiBYuanYZhangLHuLJinSet al