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123 TMAO may influence the crosstalk of different cells in the NVU and participate in the occurrence and development of neurological disorders

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On entering cells, these precursor nucleotide analogs transform into nucleotide analogs and prevent key enzymes from synthesizing DNA eventually prompting apoptosis [47]

The TEM image was offered with a magnitude 20000 and scale 500 nm

Importantly, ROS can further augment the overall antimicrobial response of PMNs by activating the release of granules, inducing the generation of neutrophil extracellular traps (NETs), and stimulating the production of the pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF) and macrophage inflammatory protein 2 (MIP-2) (Brinkmann et al., 2011