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Prior research indicates that a preservation solution supplemented with aspartate and -ketoglutarate enables renal proximal tubules to generate ATP via anaerobic metabolism and sustain mitochondrial membrane potential, thereby mitigating hypoxia-reoxygenation mitochondrial injury (91)

Dynamic CD4(+) T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection

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doi: 10.1111/j.1750-3639.1997.tb00890.x

Pyridoxal phosphate (PLP) is integral to one-carbon metabolism, a series of biochemical reactions necessary for the synthesis of nucleotides and other molecules essential for DNA and RNA production (57, 58)