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doi: 10.1016/j.ctcp.2018.03.013

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Comparatively, oral glutathione pills are considered less effective than injections due to the challenges of absorption during digestion, which may limit their efficacy

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Notably, supplementing the drinking water of these mice with the histone deacetylase inhibitor sodium butyrate delays premature cellular aging in these mutants and increases lifespan ( Histone H2B PTMs Associated With Lifespan Histone H2B monoubiquitination at lysine 123 in yeast and, correspondingly, lysine 120 in vertebrates is required for the trimethylation of both H3K4 and H3K79 (Nakanishi et al., 2009)