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In sum, while a link between iron accumulation and PD exists, the pathophysiological mechanisms of iron deposition and its effects on disease progression require additional study

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Fatty acids and iron combine, resulting in increased peroxidation of lipids and the formation of toxic substances involved in lipid peroxidation, such as the toxic and mutagenic metabolites malondialdehyde (MDA) and 4-hydroxynonenal (HNE)

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Environ Epigenet (2020) 6(1):dvaa005

Oncol Res 18:18 Yang Y, Xie Q, Zhao Z, He L, Chan L, Liu Y, Chen Y, Bai M, Pan T, Qu Y, Ling L, Chen T (2017) Functionalized selenium nanosystem as radiation sensitizer of 125I seeds for precise cancer therapy