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HouKShenJYanJZhaiCZhangJPanJAet alLoss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin

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Oxidative stress is associated with induction of neurosteroid biosynthesis in the human brain (284), and TSPO ligands ( N , N -dialkyl-2-phenylindol-3-ylglyoxylamides) that also show anxiolytic activity promote a reduction in oxidative stress and pro-inflammatory enzymes in glial cells via promotion of neurosteroid synthesis (133)

"Chelation therapy for heart disease: Does it work?" (Press release)

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Patients in the intervention group received gabapentin (24 patients, 77%), divalproex sodium (3 patients, 10%), or valproic acid (4 patients, 13%)