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Chronic administration can sometimes lead to different responses compared to acute exposure, including potential receptor desensitization or cumulative effects

When these are lacking, the signals that tell your body to relax and wind down can get disrupted, leading to restless nights and poor recovery

USA 104 , 98889893 (2007)

Dixon SJ

Although normal electron transport in mitochondria involves four-electron reduction of O 2 to water, partial reduction reactions occur under physiological conditions, causing release of superoxide anion and hydrogen peroxide (H 2 O 2 )