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Nitration of glutamate transporters can inhibit their function, increasing the likelihood of excitotoxicity (Chen et al., 2010)

This large size can impede diffusion within the dense tumor extracellular matrix, frequently restricting accumulation to perivascular regions and preventing penetration into hypoxic, acidic tumor cores, a limitation that contributes to heterogeneous therapeutic responses [221]

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Age-dependent decrease of mitochondrial complex II activity in human skin fibroblasts

doi: 10.3233/JAD-170543

Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome