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NAM also significantly increased the enzymatic activity of SOD2, a key mitochondrial antioxidant enzyme, in differentiating MC3T3-E1 osteoblast cells (Fig

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It promotes the formation of new blood vessels at injury sites, modulates nitric oxide production, and upregulates growth-hormone receptors on tendon and ligament fibroblasts

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In addition, A/R-induced increases in pMLC were attenuated by pretreatment with LA in these cells, demonstrating the role of LA in the MLC pathway of tight junction regulation

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