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Ketamine, a noncompetitive antagonist of the NMDAR, has been shown to induce rapid and significant antidepressant effects within a few hours

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The rate of transport increases nearly linearly up to a serum ketone concentration of 10 mM, accompanied by a contemporaneous reduction in cerebral glucose utilization, supporting the rapid use of ketones as energy substrates when they are available [35,36,37]

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2018 October 294 (2):e10296

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