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10.1016/j.scitotenv.2020.140429 17 ElshaghabeeF

While GSK3i may affect ERK1/2 and MTOR p70S6K at other time points, our results agree with Kuemmerles finding that in gastrointestinal smooth muscle cells, the AKT GSK3i-mediated and p70S6K- and ERK1/2-dependent mechanisms are functionally segregated, with AKT-dependent signaling being involved only in anti-apoptotic but not in the proliferation-stimulating actions of IGF1 [19,20]

The pituitary's negative feedback system prevents truly excessive GH output

Coordinacin endocrina multirreceptor Modelos de investigacin tambin analizan cmo los pptidos que actan sobre distintos sistemas receptores pueden influir en la sealizacin hormonal coordinada