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Muteeb, G., Rehman, M

Indeed, as mentioned above, hypoxia induced by vessel depletion can activate several mechanisms used by tumor cells to counteract the lack of oxygen and nutrients such as increased tumor invasiveness and co-option of normal vessels resulting in ineffective anti-angiogenic therapy

[DOI] [PubMed] [Google Scholar] 115.Trenca C.A., Koenig J.Q., Williams P.V