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Furthermore, vagus nerve stimulation attenuates peripheral and neural inflammation by suppressing the 7nAChR/JAK2/STAT3/NF-B signaling axis ( 4.5 Immunity In recent decades, substantial progress has been made in elucidating how gut microbiota regulate neuroinflammatory processes through peripheral immune mechanisms

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This holistic perspective has revealed that the use of antibiotics carries both short-term and long-term consequences for the normal gut microbial community