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The occurrence, progression and metastasis of brain tumors such as glioblastoma may be related to ferroptosis, and manipulation of iron death may provide a new strategy for the treatment of brain tumors (Figure 3)

However, in the presence of copper deficiency or ATP7A dysfunction, this regulatory mechanism falters, leading to NMDAR overactivation, calcium overload, and neuronal apoptosis (217, 218)

ROS levels directly influence synaptic efficiency, characterized as the most important origin of neuronal dysfunction in PD

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Our exhaustive review of the existing literature points to a pivotal role for cysteinea key amino acid central to hair growthin these mechanisms

Pediococcus was a homofermentative LAB (Oliveira et al., 2017)