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Rating: 4.279 (7 reviews)

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Description

IDH1 mutations cause significant changes in enzymatic reactions, catalyzing the large-scale conversion of -ketoglutarate (2-KG) to 2-hydroxyglutarate (2-HG), and cause significant changes in the cells metabolic system

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Twenty-two randomised controlled trials with 1710 participants (average intervention duration = 10 weeks) were included

This discovery paved the way for identifying various previously unknown chemical, biological, and biochemical reactions associated with O 2 , and other ROS and free radicals, as well as their biological damage mechanism and their implications for different diseases [32,33] (Figure 3 and Figure 4)

doi: 10.1111/head.13715 99

The results revealed that NGF administration significantly improved the survival of the transplanted cells, increased the DA content in local brain tissue, and led to a more significant improvement in motor function compared to cell transplantation [82]