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PTAs absorb NIR energy at specific wavelengths and convert it into thermal energy by nonradiative decay, rapidly increasing the local temperature of the tumor to a threshold lethal to its cells [266]

[] Several experimental studies were performed that aimed at checking the mechanism of cisplatin-induced apoptosis, and it showed the active role of p53, p38 mitogen-activated protein kinase (MAPK) and Jun N-terminal kinases (JNK) by altering the mitochondrial membrane potential and upregulating caspase-3 activities

Their enhanced permeability profiles reduce systemic side effects in applications such as antihypertensive and topical antibiotic delivery (Yang M

doi: 10.1146/annurev-arplant-050312-120132 47 FengH.SchorppK.JinJ.YozwiakC

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It is also employed in treating corneal diseases and eczema due to its anti-allergic properties