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Specifically, we administered a series of doses of rosiglitazone or WY-14643 (25 mg/kg body weight, 12.5 mg/kg body weight, 6.25 mg/kg body weight, 3.125 mg/kg body weight) via i.p

Acadian Asset Management (UK) Limited will only make this material available to Professional Clients and Eligible Counterparties as defined by the FCA under the Markets in Financial Instruments Directive, or to Qualified Investors in Switzerland as defined in the Collective Investment Schemes Act, as applicable.

This oxidative stress damages cellular membranes, proteins, and DNA

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5 days/week) Frequency: Once daily, 5 days per week , progressing from 1.0 mg to 1.5 mg and then 2.0 mg as shown above

(2023, October 5)