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Sesquiterpenes are agonists of the pregnane X receptor but do not induce the expression of phase I drug-metabolizing enzymes in the human liver

Natural, synthetic, or hybrid polymers can be used to make hydrogels

But what if a peptide could reverse the trend

Kupffer cells and DC, but not B cells in the Rej liver, upregulated PD-L1, PD-L2 and TREM2, a marker of immunosuppressive myeloid cells (Fig F)

These challenges arise not only from methodological heterogeneity but also from biological complexity, and they must be addressed to enable translation of mechanistic findings into clinical application

thus, SOX may be removed via other pathways and antioxidants, such superoxide dismutase and glutathione peroxidase (45, 46)