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The method was applied to pharmacokinetic and oral-bioavailability experiments in rats

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Accordingly, we employed the random forest (RF) algorithm from the open-source Python library Scikit-learn ( The interpretability of the developed RF model was further enhanced by employing the SHAP (SHapley Additive exPlanations) framework, a game-theoretic approach that elucidates the output of machine learning models 63

While chemical injections into the testis have never been proposed for use in men, this method has received huge support for inducing sterility in a variety of domesticated animals

doi: 10.1016/j.cell.2013.12.010 170 KasaikinaMVKravtsovaMALeeBCSeravalliJPetersonDAWalterJet al