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East African Scholars J Biotechnol Genet

Pyridoxines protective effects may be mediated by improved endothelial nitric oxide synthase (eNOS) function, reduction of homocysteine levels, and modulation of sympathetic activity

Our clinical philosophy emphasizes healthy, resilient skin and overall cellular well-being rather than altering natural skin color

The Fenton reaction generates free radicals that react with phospholipid-containing polyunsaturated fatty acid (PUFA-PL) chains, resulting in the formation of phospholipid hydroperoxides (PLOOHs), a hallmark of ferroptosis [74]

Decreased activity of GR could be a direct consequence of the overall depletion of antioxidantive substances and their co-factor as well as enzyme inhibition by glucose glycation due to acidosis

Future research should focus on the monitoring technology for the three-organ linkage, developing microbiota intervention strategies based on metabolic simulations, and validating a treatment paradigm that prioritizes intestinal barrier repair, liver metabolism rebalancing, and renal excretion optimization