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For AEDA, the obtained extracts were stepwise diluted with dichloromethane (starting at 1:1, then 1:2, 1:4, 1:8, 1:16, etc.)

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Thus, at each of these three stages of heme transfer, namely cell uptake, release from mitochondria and macrophage breakdown there is no necessity for heme to enter the cytosol

32371185), the Shanghai Science and Technology Plan Project (grant no