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Carbidopa is administered with levodopa to inhibit its early conversion to dopamine outside the central nervous system, thereby minimizing side effects like nausea and enhancing the quantity of levodopa penetrating the brain (47)

All authors reviewed and approved the final manuscript

Drijvers JM, Gillis JE, Muijlwijk T, Nguyen TH, Gaudiano EF, Harris IS, et al

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Stabilization of HIF in CD8+ T cells apparently can bypass inhibitory receptor signaling typically associated with the dampening of effector capacity when antigen cannot be cleared