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There were only six studies in HepG2 cells with NDMA exhibiting a negative outcome

During a study for its efficacy as a B12 supplement, hydroxocobalamin was found to show better retention over cyanocobalamin (CnCbl), was absorbed more slowly from the site of injection, maintained higher and longer blood levels, and was eliminated more slowly from urine

doi: 10.1111/j.1532-5415.1986.tb04902.x, 12

Chronic conditions or slow healers may require 16-24 weeks or longer

10.5664/jcsm.5100 108

It is important to note that dosages may vary depending on the specific research objectives, patient population, and safety considerations