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The pattern visible with SARMs, novel psychoactive substances and now peptides is that the regulatory category churns through a five-to-ten-year cycle where a new compound class enters the consumer market, builds a customer base, gets partially restricted, and then the industry pivots to the next class

Mar 8 2023;13(6):1037

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doi: 10.1016/S0014-5793(01)03007-1 75 NakataMNagasakaSKusakaIMatsuokaHIshibashiSYadaT

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Inadequate response may also be the result of medication nonadherence, which may require additional education.5 There is much we can do in primary care to enhance identification and treatment of patients with difficult-to-treat depression