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Furthermore, the terms fragment, derivative or analog are exemplified by a "pro-form molecule, such as a low activity proprotein that can be modified by cleavage to produce a mature enzyme with significantly higher activity

Mihucz VG, Meirer F, Polgri Z et al (2016) Iron overload of human colon adenocarcinoma cells studied by synchrotron-based X-ray techniques

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doi: 10.1038/nature22815 190 SunJ.XuJ.LingY.WangF.GongT.YangC.et al