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Prime Labs Bacteriostatic Water is an in-house synthesized, sterile-filtered preparation designed for the multi-dose reconstitution of lyophilized research compounds

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All TLRs, with the exception of TLR3, primarily utilize the MyD88-dependent pathway, which leads to the activation of the key transcription factor NF-B and the subsequent upregulated expression of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6

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Premsrirut PK, Dow LE, Kim SY et al (2011) A rapid and scalable system for studying gene function in mice using conditional RNA interference