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AD is biologically defined by production and aggregation of misfolded protein including extracellular amyloid (A) peptide and intracellular microtubule-associated protein tau tangles in neurons, leading to irreversible neuronal loss

Diagnosis is usually confirmed through endoscopy or imaging studies, and treatment often involves medications to reduce stomach acid and promote healing

It has shown potential for supporting the management of chronic gastrointestinal conditions, such as inflammatory bowel diseases (IBD), including ulcerative colitis (UC)

Pinealon is the neuroprotector that calms brain activity and supports serotonin pathways

Epidemiology Incidence affects ~0.2% of Caucasian population Demographics 4:1 male:female usually presents in 3rd decade of life Etiology Pathoanatomy exact mechanism is unknown, but most likely due to an autoimmune reaction to an environmental pathogen in a genetically susceptible individual

83 If the amounts of pericytes reduce, the tight junctions between endothelial cells will also be reduced