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Clinical outcomes following termination of immunotherapy due to long-term benefit in MSI-H colorectal cancer

10.1016/j.tox.2020.152532 Toxicology 22 CherraS

The hydrolysis of triglycerides into free fatty acids and monoglycerides, which are further taken in by the intestinal epithelium, can only happen with these three components, colipase, bile salts, and pancreatic lipase [64]

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The proposed mechanism involves Gsp which enhances MEG3 expression by means of phospho-CREB overexpression leading to a reduction in cell proliferation and invasiveness