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UPS dysfunction in metabolic diseases Metabolic diseases are often accompanied by heightened oxidative stress, driven by ROS produced by malfunctioning mitochondria and persistent inflammation

10.1021/acscentsci.7b00589 ACS Cent

MC is processed in laboratories and fractions of MC have been detected in natural as well as occupational and domestic environment

Larger concentrations of tGSH and GSH in the liver than in the muscle tissues were also recorded in three species of crayfish studied by Kovaevi et al

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This leads to an increase in whole body radical burden, and increased oxidative damage to cell membranes