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For example, if the hypothalamus fails to signal the pituitary gland to release ACTH, then the adrenal gland wont produce sufficient amounts of cortisol

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Converging evidence highlights mitochondrial dysfunction and oxidative stress, resulting from excessive production of reactive oxygen species (ROS) and/or insufficient antioxidant defenses, in both peripheral tissues and brain samples of individuals with ASD (Lin et al., 2022) This oxidative dysregulation is thought to exacerbate neuroinflammation, mitochondrial dysfunction, and synaptic abnormalities, which may underlie some of the core behavioral and cognitive impairments seen in ASD (Gevezova et al., 2023)

Benson, J

Rozencwaig et al

As a proof of concept, the assembly of functional AuNPs in a tumour-selective manner can mimic BiTE for precise combinational immunotherapy