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Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action Glutathione (-L-glutamyl-L-cysteinyl-glycine) acts as a redox buffer, maintaining intracellular thiol equilibrium

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doi: 10.1016/j.tifs.2020.03.018 64

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elegans exhibit elevated ROS, upregulated mito-UPR, SKN-1 and DAF-16-dependent transcription, and significantly longer lifespan 40,41