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Although cytotoxicity was not specific to homocysteine, endothelial cell detachment is also observed with cysteine (Dudman et al, 1991), an increase in the hydrogen peroxide-sensitive cellular fluorescent probe, 2,7-dichloro-fluorescein, was observed in cultured endothelial cells exposed to homocysteine (Toborek and Hennig, 1996)

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Assessing Autistic Symptoms and Severity Three tools were used by the same parent/guardian at the beginning and end of the study to assess the severity and symptoms of autism, namely the Pervasive Development Disorder Behavior Inventory (PDD-BI) [29], Autism Evaluation Treatment Checklist (ATEC) [30], and Severity of Autism Scale (SAS) [31]