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Cagrilintide copies and strengthens this effect, making it last much longer than natural amylin does

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

An easy way to combat that is actually gentle, consistent movement throughout the day

In addition, whether these effects can be sustained long-term is not known

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Martinez-Garcia E, Popovic R, Min DJ, Sweet SMM, Thomas PM, Zamborg L, Heffner A, Will C, Lamy L, Staudt LM, Levens DL, Kelleher NL, Licht JD