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TNF-, tumour necrosis factor-alpha

This profile is consistent with the function of copper as a SOD cofactor and with the observed modulation of antioxidant defense genes Profile observed in models (synthesis): Activity at the level of fibroblasts and extracellular matrix cells stimulation of the synthesis of structural proteins Copper transport function coupled with the activity of Cu-dependent enzymes Modulation of repair and antioxidant gene expression in transcriptomic studies Pro-angiogenic and pro-regenerative profile in wound healing models In research models, GHK-Cu is interpreted as bifunctional extracellular matrix modulator a signal stimulating the synthesis of connective tissue components and a carrier providing copper as a cofactor for enzymes responsible for the maturation and cross-linking of this matrix

doi: 10.1126/scitranslmed.abb0319 67

The clinical trials are being coordinated by Peters biotech company Cleara Biotech, which is closely affiliated with UMC Utrecht

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It is uncommon to not get enough vitamin B12 from your diet but can be an issue especially if you do not eat animal products and follow a vegan or strict vegetarian diet without eating B12 fortified foods or taking a supplement