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This enabled us to employ both manual gating and unsupervised clustering approaches to profile immune-phenotypes and metabolic activity of CD14 + monocytes, DC precursors (mono 24 h/48 h), immature DC (day 5 iDC), DC after 4 h LPS + IFN- (actDC), and DC after 24 h of LPS + IFN-'' (mDC) at single-cell level

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The critical concentration of vitamin E (alpha-tocopherol) in plasma is 1.12 ppm in large animals

All patients met the diagnostic criteria for sepsis as defined by the 2016 International Guidelines for the Management of Sepsis and Septic Shock, and for ALI according to the 2006 guidelines for ALI/ARDS Diagnosis and Treatment

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