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For this reason, GST-M1 null and GST-T1 null are considered high-risk genes (Strange et al

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Given the close collaboration between astrocytes and neurons in energy metabolism [135], it is plausible that lactylation, triggered by the accumulation of lactate, may play a supportive role in bolstering neuronal energy metabolism and be a crucial factor in maintaining the metabolic equilibrium necessary for the proper functioning of neural networks