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Retatrutide (LY-3437943) is a unipeptide that simultaneously activates GLP-1, GIP, and glucagon receptors

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Results Vacuolar deacidification activates autophagy flux in nutrient-rich medium Dysfunctional V-ATPase and lysosomal/vacuolar deacidification are thought to impair autophagy activity by hindering the degradative efficiency of lysosomal/vacuolar hydrolytic enzymes 16,23