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No dose-response safety curve

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This is an area of early research interest in longevity science, as maintaining genomic integrity may support overall cellular health and healthy aging pathways

They are the open edges of a mechanistic map that preclinical research has drawn with increasing precision over three decades and that remains, at its frontier, genuinely incomplete

96 UdovicicM.SeverM.KavurL.LoncaricK.BarisicI.BalenovicD.et al (2021)

Neurodegeneration triggers peripheral immune cell recruitment into the forebrain