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A meta-analysis concluded that CoQ10 supplementation effectively improves IR parameters (reducing HOMA-IR, FINS, and FBG), regulates sex hormone profiles (elevating FSH and decreasing T), and optimizes lipid metabolism (lowering TG, TC, and LDL while raising HDL levels) in women with PCOS (176)

When symptoms return early A subset of people on standard maintenance notice their symptoms come back well before the next scheduled dose