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According to the etiopathological factors, there are two types of ALS: 95% is idiopathic (sporadic) ALS and 5% is familial ALS (Delpont et al., 2020)

NMDA and AMPA receptors, VGLUT-1, VGLUT-2, EAAT-1, EAAT-2, EAAT-3 levels in hippocampi were evaluated

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Catalpol inhibits homocysteine-induced oxidation and inflammation via inhibiting Nox4/NF-B and GRP78/PERK pathways in human aorta endothelial cells