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Neurons expressing SCGN are resistant to cell death in neurodegenerative Alzheimers brain and its expression has been associated to reduced neurodegeneration and to a possible protective effect against the disease 24,26

doi: 10.1038/s41467-025-65142-y, 58 JiangH.WangJ.RogersJ.XieJ

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Studies have shown that mice lacking peroxiredoxin-1 (PRDX1), Cu, Zn-SOD (SOD1) or Mn-SOD (SOD2) present increased incidences of various malignancies (Neumann et al

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