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Description

Fish Shellfish Immunol (2021) 118:94101

Blum, S

Tom Brenna

Immunomodulatory effects of mesenchymal stem cell-derived exosomes on experimental type-1 autoimmune diabetes

The steady-state trough concentrations during IV and SC administration can be calculated using the following equations derived from the estimated parameters: Here, kel is the elimination rate constant, calculated as the ratio of CL to Vc

Furthermore, biosafety assessments based on hemolysis assays showed no remarkable cytotoxic effects at concentrations up to 400 g/mL, indicating the therapeutic potential and biocompatibility of the system (Lv et al., 2025)